News

May 19, 2016
Category: General
Posted by: antiadmin

Automated assays for biological drugs.

May 19, 2016
Category: General
Posted by: antiadmin
As of May 2016, we are no longer defined as a regional core facility.
 

Biological drug level determination with automated assays

May 19, 2016

Biological serum drug levels


Automated assays for biological drugs.

Category: General
Posted by: antiadmin

We have developed automated assays for the determination of patient serum levels of several commonly used biologicals/therapeutic antibodies. The assays are currently offered as routine assays by the Department of Medical Biochemistry at Oslo University Hospital, Radiumhospitalet. Assays for the following biologicals have so far been automated on the AutoDelfia immunoassay platform:

  • Infliximab (Remicade)
  • Adalimumab (Humira)
  • Etanercept (Enbrel)
  • Golimumab (Simponi)
  • Certolizumab pegol (Cimzia)
  • Tocilizumab (RoActemra)
  • Abatacept (Orencia)
  • Vedolizumab (Entyvio)
  • Canakinumab (Ilaris)
  • Mepolizumab (Nucala)
  • Secukinumab (Cosentyx)

Neutralizing patient antibodies, anti-drug antibodies (ADAs), to Infliximab, Adalimumab and Golimumab are also measured using automated assays. 

Requisition form for biologic drugs (in Norwegian) available on the hospital web:

http://www.oslo-universitetssykehus.no/omoss_/avdelinger_/medisinsk-biokjemi_/Documents/Rekvisisjoner/DNR-biologiske_legemidler-rekv_mars2016.pdf

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